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Fig. 4 | Cancer Cell International

Fig. 4

From: MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene

Fig. 4

Effects of forced alteration of miR-20a-5p or KIF26B expression on chemoresistance in SJSA-1 and G-292 cells. a KIF26B protein levels in 5PM- or siRNA-transfected SJSA-1 cells compared with the NC. b Cell survival rate after administering IC50 doses of drugs to SJSA-1 cells transfected with miR-20a-5p mimic (3PM) or KIF26B siRNA relative to the negative control (NC). c Levels of KIF26B protein in GFP-KIF26B-transfected cells compared with GFP control-transfected G-292 cells. d Relative cell survival rates after transfections with miR-20a-5p antagomir (5PA), GFP, or GFP-KIF26B compared with transfection with the NC in G-292 cells treated with IC50 doses of drugs. e (*p < 0.05; **p < 0.01)

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