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Fig. 8 | Cancer Cell International

Fig. 8

From: Selected polyphenols potentiate the apoptotic efficacy of glycolytic inhibitors in human acute myeloid leukemia cell lines. Regulation by protein kinase activities

Fig. 8

Effects of other polyphenols, lonidamine and glucose starvation on protein kinase activities. In (a) HL60 cells were incubated for 1 h with 5 mM 2-DG alone, or incubated for 2 or 14 h with 50 μM Gen or 8 μM Cur and then for 1 h more with or without addition of 2-DG. In (b) HL60 cells were incubated for 6 or 14 h with 100 μM Lon, or incubated for 2 h with Quer and then for 6 or 14 h more with or without addition of Lon. The temporal sequence is indicated as (x–y h) at the top of the panels. In (c) HL60 cells were maintained in complete (glucose-containing) medium (Cont), or incubated for the indicated time periods in glucose-lacking medium (Glu−), with or without Quer. For other conditions see legends of Figs. 1 and 6

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