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Fig. 1 | Cancer Cell International

Fig. 1

From: Schedule-dependent increased efficiency of pemetrexed-ionizing radiation combination therapy elicits a differential DNA damage response in lung cancer cells

Fig. 1

Optimization of the treatment schedule potentiates MTA-irradiation anticancer efficacy. a Schedule of the three tested treatment regimens differing in the duration of MTA pretreatment preceding irradiation. See text for details. b Growth curves of A549 cells during the treatment (0–3 days) and early recovery phase (up to 6 days post-treatment, e.g. day 9). c Cells exposed to the indicated treatment regimen were harvested at day 9 of the recovery phase, reseeded and cell numbers were determined at day 13 points. Data represent means of three independent experiments and bars indicate standard deviations. *P < 0.05

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