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Table 1 Demographic and clinical characteristics of patients with WHO grade IV glioma
| Characteristics | TS culture positive (n = 18) | TS culture negative (n = 17) | P value* |
|---|---|---|---|
| Age (years) | 62.6 ± 10.7 | 55.5 ± 12.9 | 0.088 |
| Sex (M:F) | 10:8 | 10:7 | 0.845 |
| Pathological diagnosis | >0.999 | ||
| GBM | 14 (77.8 %) | 15 (88.2 %) | |
| GBMO | 2 (11.1 %) | 1 (5.9 %) | |
| Gliosarcoma | 2 (11.1 %) | 1 (5.9 %) | |
| Type | >0.999 | ||
| Primary | 16 (88.9 %) | 15 (88.2 %) | |
| Recurrent | 2 (11.1 %) | 2 (11.8 %) | |
| Molecular markers | |||
| IDH1 | |||
| Wild type | 18 (100 %) | 17 (100 %) | |
| Mutation | 0 | 0 | |
| 1p19q | >0.999 | ||
| No deletion | 16 (88.9 %) | 15 (88.2 %) | |
| Codeletion | 2 (11.1 %) | 2 (11.8 %) | |
| MGMT promotor | 0.358 | ||
| Unmethylated | 10 (55.6 %) | 12 (70.6 %) | |
| Methylated | 8 (44.4 %) | 5 (29.4 %) | |
| P53 mutation | 0.443 | ||
| Wild type | 3 (16.7 %) | 5 (29.4 %) | |
| Positive by IHC | 15 (84.3 %) | 12 (70.6 %) | |
| EGFR mutation | 0.193 | ||
| Wild type | 8 (44.4 %) | 4 (23.5 %) | |
| Positive by FISH | 10 (55.6 %) | 13 (76.5 %) | |
