|
Characteristics
|
TS culture positive (n = 18)
|
TS culture negative (n = 17)
|
P value*
|
|---|
|
Age (years)
|
62.6 ± 10.7
|
55.5 ± 12.9
|
0.088
|
|
Sex (M:F)
|
10:8
|
10:7
|
0.845
|
|
Pathological diagnosis
| | |
>0.999
|
|
GBM
|
14 (77.8 %)
|
15 (88.2 %)
| |
|
GBMO
|
2 (11.1 %)
|
1 (5.9 %)
| |
|
Gliosarcoma
|
2 (11.1 %)
|
1 (5.9 %)
| |
|
Type
| | |
>0.999
|
|
Primary
|
16 (88.9 %)
|
15 (88.2 %)
| |
|
Recurrent
|
2 (11.1 %)
|
2 (11.8 %)
| |
|
Molecular markers
|
|
IDH1
|
|
Wild type
|
18 (100 %)
|
17 (100 %)
| |
|
Mutation
|
0
|
0
| |
|
1p19q
| | |
>0.999
|
|
No deletion
|
16 (88.9 %)
|
15 (88.2 %)
| |
|
Codeletion
|
2 (11.1 %)
|
2 (11.8 %)
| |
|
MGMT promotor
| | |
0.358
|
|
Unmethylated
|
10 (55.6 %)
|
12 (70.6 %)
| |
|
Methylated
|
8 (44.4 %)
|
5 (29.4 %)
| |
|
P53 mutation
| | |
0.443
|
|
Wild type
|
3 (16.7 %)
|
5 (29.4 %)
| |
|
Positive by IHC
|
15 (84.3 %)
|
12 (70.6 %)
| |
|
EGFR mutation
| | |
0.193
|
|
Wild type
|
8 (44.4 %)
|
4 (23.5 %)
| |
|
Positive by FISH
|
10 (55.6 %)
|
13 (76.5 %)
| |
- * By Independent two-sample t test for continuous variables and Chi square test (or Fisher’s exact test) for categorical variables
