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Fig. 5 | Cancer Cell International

Fig. 5

From: Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells

Fig. 5

BMP2 expression suppresses CRC growth in vivo. a Tumour formation in SCID mice after subcutaneous injection of HCT116 cells stably-expressing BMP2 or LV control cells. Data are presented as mean (tumor volume) ± S.E., n = 6. Two-way ANONA analysis was used to compare the two growth curves. b Representative histopathological examination of xenograft tumors from BMP2 and control HCT116 cells. FFPE sections were stained with haematoxylin and eosin stain. (Bar = 100 μm). Expression of MKI67 (c) and BCL2 (d) in xenograft tumors from BMP2 and control HCT116 cells is shown

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