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Table 1 Correlation of TPX2 expression with clinicopathologic features

From: Expression of microtubule-associated protein TPX2 in human gastric carcinoma and its prognostic significance

Characteristics Total (n = 106) TPX2 P value
Negative (n = 35) Positive (n = 71)
Gender
 Male 67 (63.2 %) 22 (32.8 %) 45 (67.2 %) 0.958
 Female 39 (36.8 %) 13 (33.3 %) 26 (66.7 %)
Age (years)
 ≥60 46 (43.4 %) 7 (15.2 %) 39 (84.8 %) 0.001
 <60 60 (56.6 %) 28 (46.7 %) 32 (53.3 %)
T stage
 1 10 (9.4 %) 8 (80 %) 2 (20 %) 0.003
 2 10 (9.4 %) 4 (40 %) 6 (60 %)
 3 84 (79.2 %) 22 (26.2 %) 62 (73.8 %)
 4a 2 (1.9 %) 1 (50 %) 1 (50 %)
N stage
 0 21 (19.8 %) 10 (47.6 %) 11 (35.2 %) 0.120
 1 38 (35.8 %) 14 (36.8 %) 24 (63.2 %)
 3 47 (44.3 %) 11 (6.3 %) 36 (3.6 %)
M stage
 0 99 (93.4 %) 34 (34.3 %) 65 (65.7 %) 0.421
 1 7 (6.6 %) 1 (14.3 %) 6 (85.7 %)
TNM stage
 I 13 (12.3 %) 5 (38.5 %) 8 (61.5 %) 0.144
 II 17 (16.0 %) 8 (47.1 %) 9 (52.9 %)
 III 69 (65.1 %) 22 (31.9 %) 47 (68.1 %)
 IV 7 (6.3 %) 0 (0 %) 7 (100 %)
Tumor size (cm)
 ≥5 74 (69.8 %) 24 (32.4 %) 50 (67.6 %) 1.000
 <5 32 (30.2 %) 11 (34.4 %) 21 (65.6 %)
  1. The results of immune-histochemical score were determined by the average score that given by two pathologists, immune-reactivities were scored by the intensity of staining (0, no staining; 1 weak = light yellow; 2 moderate = yellow brown; 3 strong = brown) and the percentage of stained cells (0 no staining; 1, 0–10 %; 2, 11–30 %; 3, 31–70 %; 4, >71 %). By multiplication of both values, a final score ranging between 0 and 12 was obtained. TPX2 over-expression was defined as final score more than zero