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Table 2 Cox-regression analysis of various prognostic parameters in patients for all patients

From: Expression of microtubule-associated protein TPX2 in human gastric carcinoma and its prognostic significance

Factor Univariate Multivariate
HR (95 % CI) P value HR (95 % CI) P value
Sex
 Male Reference    
 Female 0.883 (0.581–1.340) 0.558
Age
 ≥60 Reference    
 <60 2.077 (1.375–3.139) 0.001 1.561 (1.009–2.417) 0.046
Tumor size (cm)
 <5 Reference    
 ≥5 2.277 (1.410–3.678) 0.001 2.091 (1.249–3.502) 0.005
TPX2 expression
 Negative Reference    
 Positive 3.703 (2.303–5.956) 0.001 4.708 (2.800–7.917) 0
AJCC tumor stage
 I Reference    
 II 1.971 (0.840–4.624) 0.119
 III 2.268 (1.081–4.756) 0.030
 IV 2.666 (0.963–7.382) 0.059
N stage
 0 Reference    0
 1 4.022 (1.955–8.274) 0.000 3.122 (1.474–6.611) 0.003
 3 7.015 (3.421–14.386) 0.000 5.858 (2.731–12.566) 0
Distant metastasis
 No Reference    
 Yes 0.855 (0.346–2.110) 0.733
Infiltration
 No Reference    
 Yes 2.023 (0.639–6.402) 0.231