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Fig. 6 | Cancer Cell International

Fig. 6

From: Alpha-synuclein contributes to malignant progression of human meningioma via the Akt/mTOR pathway

Fig. 6

Depletion of α-synuclein (α-Syn) retards tumor growth in a mouse xenograft model. IOMM-Lee cells stably transfected with α-Syn shRNA or control shRNA were subcutaneously injected into nude mice (n = 4) and tumor volumes were measured every 5 days. a Tumor growth curves based on tumor volumes. b Tumors were resected and weighed at 25 days after cell injection. c Immunohistochemical staining for Ki-67 in the tumors. Top representative images of tissue sections stained for Ki-67. Bottom quantitative analysis of Ki-67-positive cells. Scale bars 100 μm. *P < 0.05

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