Fig. 6From: Alpha-synuclein contributes to malignant progression of human meningioma via the Akt/mTOR pathwayDepletion of α-synuclein (α-Syn) retards tumor growth in a mouse xenograft model. IOMM-Lee cells stably transfected with α-Syn shRNA or control shRNA were subcutaneously injected into nude mice (n = 4) and tumor volumes were measured every 5 days. a Tumor growth curves based on tumor volumes. b Tumors were resected and weighed at 25 days after cell injection. c Immunohistochemical staining for Ki-67 in the tumors. Top representative images of tissue sections stained for Ki-67. Bottom quantitative analysis of Ki-67-positive cells. Scale bars 100 μm. *P < 0.05Back to article page