Skip to main content

Table 4 Top 5 enriched GO terms (BP, CC, and MF) from the microarray data

From: Comprehensive analysis of the long noncoding RNA HOXA11-AS gene interaction regulatory network in NSCLC cells

GO.ID

Term

Ontology

Enrichment score

P

Upregulated genes

 GO:0071294

Cellular response to zinc ion

BP

8.557911479

2.76751E−09

 GO:0044707

Single-multicellular organism process

BP

8.514757717

3.05663E−09

 GO:0048731

System development

BP

8.400063137

3.98049E−09

 GO:0032501

Multicellular organismal process

BP

8.203661346

6.2566E−09

 GO:0048856

Anatomical structure development

BP

8.143712557

7.1827E−09

 GO:0005578

Proteinaceous extracellular matrix

CC

8.300801864

5.00263E−09

 GO:0031012

Extracellular matrix

CC

8.221562341

6.00396E−09

 GO:0005604

Basement membrane

CC

6.791104942

1.61769E−07

 GO:0044420

Extracellular matrix part

CC

5.570158827

2.69055E−06

 GO:0005576

Extracellular region

CC

5.516943306

3.04128E−06

 GO:0005102

Receptor binding

MF

8.517557576

3.03698E−09

 GO:0008083

Growth factor activity

MF

7.9661485

1.08106E−08

 GO:0005178

Integrin binding

MF

4.513665828

3.06432E−05

 GO:0030414

Peptidase inhibitor activity

MF

4.359313435

4.37206E−05

 GO:0061134

Peptidase regulator activity

MF

4.350560953

4.46107E−05

Downregulated genes

 GO:0001707

Mesoderm formation

BP

4.07566169

8.40114E−05

 GO:0048332

Mesoderm morphogenesis

BP

4.002278949

9.94766E−05

 GO:0016331

Morphogenesis of embryonic epithelium

BP

3.806552741

0.000156116

 GO:0048729

Tissue morphogenesis

BP

3.403951508

0.000394501

 GO:0002064

Epithelial cell development

BP

3.374049298

0.000422621

 GO:0060076

Excitatory synapse

CC

4.66716144

2.15198E−05

 GO:0034364

High-density lipoprotein particle

CC

2.577293133

0.002646713

 GO:0048786

Presynaptic active zone

CC

2.543382451

0.002861657

 GO:0034358

Plasma lipoprotein particle

CC

2.241145559

0.005739241

 GO:0032994

Protein-lipid complex

CC

2.196499993

0.006360628

 GO:0008201

Heparin binding

MF

3.006284448

0.000985634

 GO:0005539

Glycosaminoglycan binding

MF

2.534599082

0.002920121

 GO:0004867

Serine-type endopeptidase inhibitor activity

MF

2.466282926

0.003417567

 GO:1901681

Sulfur compound binding

MF

2.39941613

0.003986427

 GO:0004866

Endopeptidase inhibitor activity

MF

1.829660366

0.014802656