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Fig. 10 | Cancer Cell International

Fig. 10

From: Autophagy induced by a sulphamoylated estrone analogue contributes to its cytotoxic effect on breast cancer cells

Fig. 10

Western blot analysis of LC3II protein expression levels. Western blots of ai MCF-7 and aii MDA-MB-231 cells treated with ESE-15-ol showed a more prominent LC3II band than cells treated with ES-15-ol with 3MA. b Graphical representation demonstrates a statistically significant decrease in LC3II protein levels within cells exposed to ESE-15-ol concurrently with 3MA as well as tamoxifen with 3MA. Bars represent averages of three biological repeats (P value <0.05; standard deviations represented by T-bars; *indicates statistical differences between compounds and DMSO vehicle control; #indicates statistical difference between ESE-15-ol and ESE-15-ol with 3MA; indicates statistical difference between tamoxifen and tamoxifen with 3MA)

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