Table 3 Apoptotic nuclei evaluation by TUNEL assay in Me-45 cells after exposition to betulin derivatives in concentration 6 µM in 72 h after treatment
From: Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45)
Compound | % of cells with stained nuclei |
|---|---|
control cells | 0 |
Betulin‐l ‐Lys‐NH2 | 86 |
Betulin‐l ‐Orn‐NH2 | 100 (cells damage, reduced number of cells) |
Betulin‐l ‐Dab‐NH2 | 34 |
Betulin‐l ‐Dap‐NH2 | 48 |
Betulin‐l ‐Ala‐NH2 | 78 |
Betulin | 27 |
Betulinic acid | 95 |