Fig. 4

MiR-32 targeted FBXW7. a The miR-32 binding site in FBXW7 3′-UTR, located 286-292 bp upstream of the FBXW7 3′-UTR. b The relative luciferase activity in miR-32 mimic group and NC group. c The relative expression of FBXW7 in miR-32 mimic transfected group and NC group. Bars represent the mean of three independent experiments performed three times ±SD. d Western blot analysis of FBXW7 protein levels in miR-32 overexpressing and NC cells. *P < 0.05