MicroRNA-32 promotes cell proliferation, migration and suppresses apoptosis in breast cancer cells by targeting FBXW7

Table 1 Association of FBXW7 mRNA or miR-32 expression with clinicopathological data from breast cancer patients by quantitative PCR

Characteristics	N	miR-32		FBXW7
Characteristics	N	Relative expression level	P value	Relative expression level	P value
Age (year)
≤50	16	3.84 ± 2.84	0.100	1.11 ± 1.29	0.147
>50	11	2.26 ± 1.37		0.49 ± 0.42
Tumor size (cm)
≤2	5	3.05 ± 0.59	0.969	0.56 ± 0.46	0.631
>2 and ≤5	14	3.31 ± 3.13		0.66 ± 0.71
>5	8	3.08 ± 1.94		1.01 ± 1.34
ER status
Negative	7	4.05 ± 4.26	0.509	1.08 ± 1.48	0.454
Positive	20	2.89 ± 1.45		0.62 ± 0.63
PR status
Negative	7	1.88 ± 0.90	0.100	1.18 ± 1.42	0.324
Positive	20	3.65 ± 2.66		0.59 ± 0.64
HER-2 status
Negative	3	2.10 ± 1.41	0.885	0.38 ± 0.09	0.479
Positive	24	3.22 ± 2.57		0.79 ± 0.96
Lymph node status
Negative	12	3.82 ± 3.36	0.24	0.70 ± 1.14	0.817
Positive	15	2.69 ± 1.28		0.78 ± 0.73
Clinical stage
I–II	19	3.32 ± 2.85	0.695	0.85 ± 1.05	0.369
III–IV	8	2.90 ± 1.13		0.49 ± 0.44
Ki-67
Negative	2	3.27 ± 1.23	0.965	0.54 ± 0.23	0.749
Positive	25	3.19 ± 2.53		0.76 ± 0.95