Fig. 7

Impact of miR-335 on GC cell migration, invasion, and proliferation. a, b Wound-healing assay in SGC-7901 cells. Quantitative values indicate the mean distance ± SD between the migration fronts measured at different time-points per three wells, and are representative of three experiments. Cells treated with 5-aza closed the wound significantly slower than untreated cells. *P < 0.05 between groups. c Cell proliferation of 5-aza-treated SGC-7901 and MKN-45 cells was assessed by MTT assay. Values are expressed as the mean ± SD of three experiments. Cell proliferation was significantly lower in SGC-7901 and MKN-45 cells treated with 5-aza compared with untreated and parental cells. *P < 0.05