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Table 1 The correlation between expression levels of miR-335 in GC specimens and GC clinicopathologic features

From: Up-regulation of CRKL by microRNA-335 methylation is associated with poor prognosis in gastric cancer

  Low expression (n = 115) High expression (n = 116) P
n % n %
Age      0.728
 >55 87 76 90 78  
 ≤55 28 24 26 22  
Sex      0.641
 Male 63 55 60 52  
 Female 52 45 56 48  
Histological grade      0.616
 Well 39 34 43 37  
 Poor 76 66 73 63  
Tumor size (cm)      0.030*
 ≤3.5 24 21 39 34  
 >3.5 91 79 77 66  
Macroscopic type      0.702
 Early stage 3 3 3 3  
 Borrmann I + II 10 9 14 12  
 Borrmann III + IV 102 88 99 85  
Lauren's grade      0.813
 Intestinal 36 31 38 33  
 Diffuse 79 69 78 67  
Venous invasion      0.027*
 Absent 81 70 96 83  
 Present 34 30 20 17  
Liver metastasis      0.669
 Absent 105 91 104 90  
 Present 10 9 12 10  
Peritoneal dissemination      0.027*
 Absent 95 83 107 92  
 Present 20 17 9 8  
pT stage      0.040*
 T1 1 1 5 4  
 T2 20 17 24 21  
 T3 30 26 42 36  
 T4 64 56 45 39  
pN stage      0.038*
 N0 + N1 29 25 44 38  
 N2 + N3 86 75 72 62  
Metastasis lymph node      0.033*
 Negative 26 23 41 35  
 Positive 89 77 75 65  
Invasion into lymphatic vessels      0.041*
 Negative 87 76 100 86  
 Positive 28 24 16 14  
AJCC stage      0.005*
 I + II 48 42 70 60  
 III + IV 67 58 46 40  
  1. Based on Pearson χ 2 test and Fisher exact test
  2. pT primary tumor, pN primary node, AJCC American Joint Committee on Cancer
  3. * Statistically significant