Fig. 2

VEGFA expression was up-regulated in MMQ tumor stem-like cells and human prolactinoma tumor sphere cells. a VEGFA mRNA expression in MMQ TSLCs significantly increased compared with that in MMQ cells. b The VEGFA level of culture medium supernatant from MMQ TSLCs was higher than that from MMQ cells. c The protein expression of VEGFA significantly increased in MMQ TSLCs compared with MMQ cells evaluated by WB. d Human prolactinoma tumor spheres cultured in serum-free suspension medium had higher VEGFA mRNA, evaluated by qRT-PCR, compared with the original generation cells. e The expression of VEGFA protein of human prolactinoma tumor spheres was also significantly increased compared with that of the original generation cells. TSLC tumor stem-like cell, T human prolactinoma tumor spheres, O original generation cells of human prolactinoma. **P < 0.01