Table 1 Biological processes analysis of the gene expression profiles
From: Global expression profile of tumor stem-like cells isolated from MMQ rat prolactinoma cell
Geneset name | Genes in geneset | Description | Genes in overlap (k) | k/K | P value |
|---|---|---|---|---|---|
Pathway in cancer | 317 | Genes annotated by the KEGG rno05200:pathways in cancer | 25 | 0.07886 | 0.0159 |
MAPK signaling pathway | 266 | Genes annotated by the KEGG rno04010:MAPK signaling pathway | 21 | 0.07895 | 0.0281 |
Regulation of action cytoskeleton | 209 | Genes annotated by the KEGG rno04810:regulation of action cytoskeleton | 19 | 0.09091 | 0.0106 |
Focal adhesion | 195 | Genes annotated by the KEGG rno04510:focal adhesion | 20 | 0.10256 | 0.0023 |
Tight junction | 130 | Genes annotated by the KEGG rno04530:tight junction | 17 | 0.13077 | 0.0004 |
Cell cycle | 126 | Genes annotated by the KEGG rno04110:cell cycle | 18 | 0.14286 | 8.7916E−05 |
Leukocyte transendothelial migration | 115 | Genes annotated by the KEGG rno04670:leukocyte transendothelial migration | 14 | 0.12174 | 0.0031 |
Oocyt meiosis | 111 | Genes annotated by the KEGG rno04114:oocyt meiosis | 12 | 0.10811 | 0.0163 |
TGF-beta signaling pathway | 86 | Genes annotated by the KEGG rno04350:TGF-beta signaling pathway | 11 | 0.12791 | 0.0075 |
Glycolysis/gluconeogenesis | 84 | Genes annotated by the KEGG rno00010:glycolysis/gluconeogenesis | 10 | 0.11905 | 0.018 |
p53 signaling pathway | 66 | Genes annotated by the KEGG rno04115:p53 signaling pathway | 11 | 0.16667 | 0.001 |
Glutathione metabolism | 50 | Genes annotated by the KEGG rno00480:glutathione metabolism | 7 | 0.14 | 0.0306 |
Valine leucine and isoleucine degradation | 46 | Genes annotated by the KEGG rno00280:valine leucine and isoleucine degradation | 7 | 0.15217 | 0.0211 |
Fatty acid metabolism | 42 | Genes annotated by the KEGG rno00071:fatty acid metabolism | 6 | 0.14286 | 0.0481 |
Butanoate metabolism | 33 | Genes annotated by the KEGG rno00650:butanoate metabolism | 7 | 0.21212 | 0.0042 |