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Table 2 Genotype distributions and allele frequencies of RAGE polymorphisms between cases and controls

From: Effect of RAGE gene polymorphisms and circulating sRAGE levels on susceptibility to gastric cancer: a case–control study

Model Controls (N = 207) Cancer (N = 200) Adjusted OR (95% CI)a P
rs2070600
 GG 136 (0.657) 113 (0.565) 1.00ref  
 AG 58 (0.280) 72 (0.360) 1.62 (1.03–2.58) 0.038
 AA 13 (0.063) 15 (0.075) 1.27 (0.54–2.98) 0.581
 A allele 84 (0.203) 102 (0.255) 1.00ref  
 G allele 330 (0.797) 298 (0.745) 1.37 (0.96–1.95) 0.082
AG + AA vs. GG    1.56 (1.01–2.39) 0.044
AA vs. AG + GG    1.09 (0.47–2.51) 0.841
rs184003
 GG 138 (0.667) 148 (0.740) 1.00ref  
 GT 64 (0.309) 48 (0.240) 0.62 (0.39–0.99) 0.048
 TT 5 (0.024) 4 (0.020) 1.02 (0.24–4.27) 0.984
 G allele 340 (0.821) 344 (0.860) 1.00ref  
 T allele 74 (0.179) 56 (0.140) 0.72 (0.48–1.08) 0.107
GT + TT vs. GG    0.64 (0.41–1.02) 0.060
TT vs. GT + GG    1.15 (0.28–4.81) 0.849
rs1800624
 TT 166 (0.802) 150 (0.750) 1.00ref  
 AT 35 (0.169) 42 (0.210) 1.40 (0.83–2.39) 0.210
 AA 6 (0.029) 8 (0.040) 1.03 (0.32–3.35) 0.961
 T allele 367 (0.886) 342 (0.855) 1.00ref  
 A allele 47 (0.114) 58 (0.145) 1.25 (0.81–1.94) 0.319
AA + AT vs. TT    1.34 (0.82–2.21) 0.246
AA vs. AT + TT    0.97 (0.30–3.12) 0.952
rs1800625
 CC 1 (0.005) 3 (0.015) 1.00ref  
 CT 22 (0.106) 13 (0.065) 0.25 (0.02–2.97) 0.275
 TT 184 (0.889) 184 (0.920) 0.44 (0.04–4.70) 0.500
 C allele 24 (0.058) 19 (0.048) 1.00ref  
 T allele 390 (0.942) 381 (0.953) 1.33 (0.69–2.54) 0.393
TT + CT vs. CC    0.42 (0.04–4.45) 0.473
TT vs. CT + CC    1.52 (0.75–3.08) 0.245
  1. Italic values indicate a significant difference
  2. aAdjusted for gender, age, BMI, family history of cancer, ethnicity, smoking and drinking status