Table 4 The association between RAGE gene polymorphisms and sRAGE levels
Polymorphisms | Controls (N = 90) | Cancer (N = 90) | ||
|---|---|---|---|---|
sRAGE levels (pg/ml) | P value | sRAGE levels (pg/ml) | P value | |
sRAGE levels (mean ± SD) | 108.31 ± 132.97 | 56.86 ± 147.74 | 0.015 | |
rs2070600 | ||||
GG | 133.72 ± 137.73 | 1.00ref | 90.56 ± 183.54 | 1.00ref |
AG | 49.13 ± 104.88 | 0.010 | 10.96 ± 39.47 | 0.024 |
AA | 27.22 ± 30.56 | 0.130 | 0.00 ± 0.00 | 0.171 |
rs184003 | ||||
GG | 89.68 ± 114.24 | 1.00ref | 32.46 ± 77.92 | 1.00ref |
GT | 145.13 ± 160.93 | 0.071 | 119.50 ± 254.34 | 0.016 |
TT | 379.64 ± 0.00 | 0.014 | 124.63 ± 200.63 | 0.044 |
rs1800624 | ||||
TT | 98.32 ± 132.76 | 1.00ref | 45.23 ± 117.97 | 1.00ref |
AT | 171.68 ± 138.67 | 0.072 | 49.72 ± 92.55 | 0.872 |
AA | 84.75 ± 63.20 | 0.840 | 203.13 ± 393.90 | 0.022 |
rs1800625 | ||||
CC | 105.09 ± 0.00 | 1.00ref | 0.00 ± 0.00 | 1.00ref |
CT | 34.82 ± 34.43 | 0.089 | 5.29 ± 13.99 | 0.545 |
TT | 116.62 ± 138.25 | 0.934 | 63.50 ± 155.47 | 0.484 |