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Table 3 Stratified analysis of rs35301225 genotype in clinical characteristic of gastric cancer patients

From: rs35301225 polymorphism in miR-34a promotes development of human colon cancer by deregulation of 3′UTR in E2F1 in Chinese population

Feather

Genotype

CC vs. AA

P value*

CC vs. A carrier

P value*

CC

CA

AA

A carrier

Age (years)

 ≤50

99

81

196

277

0.258

0.4399

 >50

90

74

145

219

 

Gender

 Male

80

69

169

238

0.11

0.1990

 Female

109

86

172

258

 

Differentiation grade

 Well

102

75

72

147

<0.0001

<0.0001

 Moderate

48

69

74

143

 Poor

39

11

195

206

 

Tumor size (cm)

 ≤5

157

144

177

321

<0.0001

<0.0001

 >5

32

11

164

175

 

Metastasis

 Yes

147

134

131

265

<0.0001

 

 No

42

21

210

231

<0.0001

  1. * Two-sided Chi square test for either genotype distributions or allele frequencies between cases and controls