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Fig. 6 | Cancer Cell International

Fig. 6

From: Dual roles of extracellular signal-regulated kinase (ERK) in quinoline compound BPIQ-induced apoptosis and anti-migration of human non-small cell lung cancer cells

Fig. 6

The effect of BPIQ on the invasion of NSCLC cells. The Boyden’s chamber assay was performed to examine the effect of BPIQ on cellular invasion, a cells were treated with indicated concentrations of BPIQ for 16 h and invaded cells were analyzed using a modified Boyden’s chamber. Cells in serum-free DMEM-F12 were added to the upper chamber and allowed to migrate through 8-μm porous membrane toward a lower chamber in medium with serum. b The cellular motility was quantified by counting the number of cells that invaded to the undersides of the membrane under a microscopy (magnification: 100×). The results are presented as mean ± SD of triplicate experiments, *p < 0.05 and **p < 0.01 against vehicle respectively

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