Repression of GPRC5A is associated with activated STAT3, which contributes to tumor progression of head and neck squamous cell carcinoma

Table 1 GPRC5A expression and clinicopathologic features in HNSCC

Characteristic	Case number	GPRC5A staining score		Non-parametric tests value	P value
Characteristic	Case number	Mean	Std. error	Non-parametric tests value	P value
Gender
Male	47	38.12	5.56	Z = −0.213	0.831
Female	39	30.41	4.32
Smoking history
Yes	30	33.80	7.03	Z = −0.082	0.935
No	56	35.07	5.77
Drinking history
Yes	22	36.50	9.14	Z = −0.203	0.839
No	64	33.98	5.15
Lymph node metastasis
Yes	56	41.86	9.14	Z = −0.390	0.696
No	30	30.75	4.78
T stage
T1	22	20.27	3.76	χ² = 0.522	0.470
T2	36	28.61	5.70
T3	13	46.38	15.18
T4	15	59.93	14.61
TNM stage
I	20	17.9	3.33	χ² = 1.312	0.252
II	24	29.0	6.26
III	21	39.9	9.67
IV	21	51.6	12.66
Degree of tumor differentiation
Well	33	58.5	8.63	χ² = 17.831	<0.001*
Moderately	45	22.5	4.12
Poorly	8	3.75	1.26

ISSN: 1475-2867