Skip to main content
Fig. 9 | Cancer Cell International

Fig. 9

From: miR-484 suppresses proliferation and epithelial–mesenchymal transition by targeting ZEB1 and SMAD2 in cervical cancer cells

Fig. 9

The inverse correlation between the expression of miR-484 and ZEB1/SMAD2 in cervical cancer tissues and cell lines. a RT-qPCR showing the expression of SMAD2 and ZEB1 in 15 pairs of human cervical cancer tissues and the adjacent noncancerous tissues. U6 snRNA was used as the internal control. b Pearson’s correlation analysis indicated the negative correlation between the expression of miR-484 and ZEB1 (r = −0.55*) and SMAD2 (r = −0.65***). c RT-qPCR showing the expression of miR-484, SMAD2 and ZEB1 in cervical cancer cell lines compared with NCx. U6 snRNA and β-actin were used as the internal controls. d Western blot were used to detect the ZEB1 and SMAD2 protein levels in cervical cancer cell lines compared with NCx. All data represent mean ± SD of three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. e Representative IHC images showing the expression level of SMAD2 and ZEB1 in cervical cancer and normal cervix (×20)

Back to article page