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Table 1 Baseline characteristics of patients with metastatic NB (N = 81)

From: MYCN amplification predicts poor prognosis based on interphase fluorescence in situ hybridization analysis of bone marrow cells in bone marrow metastases of neuroblastoma

Characteristics

Total n (%)

Age (months)

 <12

3 (3.7)

 12–18

4 (4.9)

 18–24

11 (13.6)

 >24

63 (77.8)

Gender

 Male

51 (63.0)

 Female

30 (37.0)

Treatment group

 LR

3 (3.7)

 IR

3 (3.7)

 HR

75 (92.6)

Clinical stage

 IV

81 (100)

MYCN gene

 Amplification

13 (16.0)

 Normal

68 (84.0)

LDH (IU/L)

 <1500

55 (67.9)

 ≥1500

26 (31.1)

NSE (UG/L)

 <100

10 (12.3)

 ≥100

71 (87.7)

Primary site

 Abdomen

73 (90.1)

 Thorax

6 (7.4)

 Others

2 (2.5)

Event

 No event

54 (66.7)

 Relapse

20 (24.7)

 Death

7 (8.6)

  1. NB neuroblastoma, LR low-risk, IR intermediate-risk, HR high-risk, LDH lactate dehydrogenase, NSE neuron specific enolase