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Table 1 Baseline characteristics of patients with metastatic NB (N = 81)

From: MYCN amplification predicts poor prognosis based on interphase fluorescence in situ hybridization analysis of bone marrow cells in bone marrow metastases of neuroblastoma

Characteristics Total n (%)
Age (months)
 <12 3 (3.7)
 12–18 4 (4.9)
 18–24 11 (13.6)
 >24 63 (77.8)
Gender
 Male 51 (63.0)
 Female 30 (37.0)
Treatment group
 LR 3 (3.7)
 IR 3 (3.7)
 HR 75 (92.6)
Clinical stage
 IV 81 (100)
MYCN gene
 Amplification 13 (16.0)
 Normal 68 (84.0)
LDH (IU/L)
 <1500 55 (67.9)
 ≥1500 26 (31.1)
NSE (UG/L)
 <100 10 (12.3)
 ≥100 71 (87.7)
Primary site
 Abdomen 73 (90.1)
 Thorax 6 (7.4)
 Others 2 (2.5)
Event
 No event 54 (66.7)
 Relapse 20 (24.7)
 Death 7 (8.6)
  1. NB neuroblastoma, LR low-risk, IR intermediate-risk, HR high-risk, LDH lactate dehydrogenase, NSE neuron specific enolase