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Fig. 7 | Cancer Cell International

Fig. 7

From: MicroRNA-338-3p suppresses cell proliferation and induces apoptosis of non-small-cell lung cancer by targeting sphingosine kinase 2

Fig. 7

Over-expression of SphK2 lacking the 3′-UTR restores the effects of miR-338-3p on NSCLC cell proliferation and apoptosis. NSCLC cell line was co-transfected with miR-338-3p and pcDNA3.1-SphK2 without the 3′-UTR. GAPDH was an endogenous reference; NC, cells transfected with negative control. a SphK2 expression was measured using western blots for each group. b–d Cell proliferation by CCK-8 assays and by colony formation assays, cell apoptosis by flow cytometry assays (*p < 0.05)

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Cancer Cell International

ISSN: 1475-2867

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