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Fig. 4 | Cancer Cell International

Fig. 4

From: The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells

Fig. 4

27-OHC induces cell proliferation via ERβ. Cell proliferation assay in RWPE-1 (a), LNCaP (b) and PC3 (c) cells demonstrates attenuation of 27-OHC-induced cell proliferation with PHTPP treatment. Cells were treated with 1 µM 27-OHC and 10 µM PHTPP. Readings were recorded 48 h after treatments. Data is expressed as mean ± SEM. **p < 0.01; ***p < 0.001 versus controls, ##p < 0.01; ###p < 0.001 versus 27-OHC only treatment

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