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Table 2 Significantly regulated genes in absolute fold change

From: The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells

Genes

RWPE-1

LNCaP

PC3

CBX1(M)

0.9956

1.0503

1.2222*

CBX5(M)

1.1252

1.0153

1.2895**

CTGF(M)

0.8859

3.5324*

1.4869**

CYP27A1(C)

0.5065

N/E

1.2263**

FOXA1(N)

1.1357

1.1356

1.1534**

GLI2(S)

0.9029

0.8980

1.3012***

GLI3(S)

0.9287

0.9672

1.1714*

IGFBP3(M)

0.9773

2.3619*

1.1511

INSIG2(O)

0.9938

1.1923*

1.1851

MDM2(T)

1.0007

1.0855

1.2051*

MTA3(M)

1.0713

1.1684

1.2135**

NR1H2(N)

0.9437

1.1690*

1.1723

OSBP(O)

1.1333

1.1635

1.2088*

PTCH1(S)

0.9376

1.3609

1.3304*

RXRB(N)

1.1306

1.2035*

1.2004**

SREBF1(C)

0.6093

0.6811*

1.1461

SIRT1(N)

0.9817

1.1805

1.2671*

SPARC(M)

0.9115

1.0014

0.8155***

TFF1(N)

1.8358*

1.3250

1.0190

TMPRSS2(N)

1.4082*

0.8474*

1.1262

  1. N/E not expressed
  2. * p < 0.05, ** p < 0.01, *** p < 0.001 versus controls
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Cancer Cell International

ISSN: 1475-2867

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