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Table 1 Average optic density in xenografts formed by MCF-7 cells pre-cultured in 2D and 3D systems (IOD/area)

From: Growth of MCF-7 breast cancer cells and efficacy of anti-angiogenic agents in a hydroxyethyl chitosan/glycidyl methacrylate hydrogel

Group

n

CD34

VEGF-A

PDGF-B

bFGF

2D

5

0.087 ± 0.001

0.131 ± 0.003

0.156 ± 0.005

0.165 ± 0.007

3D

5

0.104 ± 0.003a

0.148 ± 0.002a

0.159 ± 0.006b

0.167 ± 0.004b

  1. Data presented as mean ± SD
  2. aP < 0.05
  3. bP > 0.05