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Table 2 Effects of Endostar and Bevacizumab on xenografts formed by MCF-7 cells pre-cultured in 3D systems (IOD/area)

From: Growth of MCF-7 breast cancer cells and efficacy of anti-angiogenic agents in a hydroxyethyl chitosan/glycidyl methacrylate hydrogel

Group

n

CD34

VEGF-A

PDGF-B

bFGF

Control

5

0.082 ± 0.002

0.134 ± 0.006

0.128 ± 0.008

0.157 ± 0.008

Endostar

5

0.070 ± 0.003a

0.116 ± 0.003a

0.124 ± 0.009b

0.155 ± 0.010b

Bevacizumab

5

0.074 ± 0.004a

0.119 ± 0.005a

0.126 ± 0.011b

0.140 ± 0.007a

  1. aP < 0.05
  2. bP > 0.05