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Table 2 Distribution of frequency of CD34+ and VEGFR2+ vessels in human breast cancer stroma (all histologic subtypes)

From: Differential expression of VEGFR2 protein in HER2 positive primary human breast cancer: potential relevance to anti-angiogenic therapies

No. of marker+ tumor stromal vessels/TMA core

0

1–5

6–10

>10

Mean # vessels/TMA core (range)

Total number of evaluable cores

CD34+ tumor vessels

9

36

52

89

11 (0–45)

186

VEGFR2+ tumor vessels

42

90

29

8

3.4 (0–20)

169

  1. About half of the evaluable TMA cores exhibited more than 10 CD34+ vessels in the tumor stroma. About half the evaluable TMA cores had lower number (1–5) of VEGFR2+ vessels/TMA core, while about a quarter of cases had no VEGFR2 expressing vessels in the tumor stroma