Fig. 4

PD98059 (25 µM) partially blocks BBR (100 µM)—regulated protein expression of tumor suppressor genes and oncogenes. a, d HepG2, b, e Hep3B and c, f SNU-182. All experiments were repeated 3 times (n = 3). All data are shown as mean ± SEM (error bars), (*p < 0.05; **p < 0.01 vs. control), (^# p < 0.05, ^## p < 0.01 vs BBR 100 μM)