Fig. 1

miR-222influence on migration and invasion of HCT8 cells. a, b Transwell migration (n = 4) and invasion (n = 4) assays showed that HCT8 cells transfected with the miR-222 mimics (800 nM) had higher invasive and migratory potentials than the control (mimics control). a A microscopic image of crystal violet staining. b The statistical results. c, d Transwell migration (n = 4) and invasion (n = 4) assays showed that HCT8 cells transfected with the miR-222 inhibitor (800 nM) had lower invasive and migratory potentials than the control (inhibitor control). c A microscopic image of crystal violet staining. d The statistical results. Data represent the mean ± SD of four independent experiments. *P < 0.05