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Fig. 1 | Cancer Cell International

Fig. 1

From: Ribonucleic acid interference knockdown of IL-6 enhances the efficacy of cisplatin in laryngeal cancer stem cells by down-regulating the IL-6/STAT3/HIF1 pathway

Fig. 1

Increased IL-6, STAT3 and HIF1 mRNA (ac) and protein (dg) levels in hep2-CSC as compared with those from the hep2 cells or laryngeal cancer tissues. The relative IL-6, STAT3 and HIF1 mRNA expression levels were significantly increased in hep2-CSC as compared to the hep2 cells or cancer tissues (p < 0.001). GAPDH served as a house-keeping gene. Consistently, IL-6, STAT3 and HIF1 protein levels were increased in hep2-CSC as compared to controls. Actin was used to normalize protein levels. **p < 0.01, ***p < 0.001 vs hep2-CSC control; ##p < 0.01 vs hep2

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