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Fig. 5 | Cancer Cell International

Fig. 5

From: Ribonucleic acid interference knockdown of IL-6 enhances the efficacy of cisplatin in laryngeal cancer stem cells by down-regulating the IL-6/STAT3/HIF1 pathway

Fig. 5

Cisplatin increases the pro-apoptotic effect of siRNA-IL-6. Representative images showing apoptosis in control (a), siRNA-IL-6-treated (b), cisplatin-treated (c), and siRNA-IL-6 and cisplatin-treated (d) hep2-CSC. Relative apoptosis rates (e) were slightly promoted by siRNA-IL-6 or cisplatin-treated hep2-CSC. The combination of cisplatin and siRNA-IL-6 significantly increased the pro-apoptotic effect of siRNAIL-6 or cisplatin. **p < 0.01 vs hep2-CSC control

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