SNP rs3202538 in 3′UTR region of ErbB3 regulated by miR-204 and miR-211 promote gastric cancer development in Chinese population

Table 4 Stratified analysis of genotypes of ErbB3 rs3202538 with clinicopathological parameters of GC

Features	Genotype			GG vs GT P value*	GG vs TT P value*
Features	GG	GT	TT	GG vs GT P value*	GG vs TT P value*
Age (years)				0.167	0.081
≤50	81	161	134
>50	97	156	222
Gender				0.416	0.756
Male	75	137	145
Female	103	219	211
Hp. infection				0.002	0.169
Negative	48	129	77
Positive	130	188	279
Differentiation grade				0.0047	<0.0001
Well	73	94	47
Moderate	68	117	120
Poor	37	106	189
Tumor size (cm)				0.109	<0.0001
≤3	93	164	19
>3	85	153	337
Metastasis				0.0042	<0.0001
Yes	49	128	235
No	129	189	121

* Two-sided Chi square test for either genotype distributions or allele frequencies between cases and controls

ISSN: 1475-2867