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Fig. 4 | Cancer Cell International

Fig. 4

From: The role of pparγ and autophagy in ros production, lipid droplets biogenesis and its involvement with colorectal cancer cells modulation

Fig. 4

Effects of autophagy and PPARγ modulation in Caco-2 cells. a Activation of PPARγ and inhibition of autophagy reduce the cell viability and induce cell death by apoptosis in Caco-2 cells. b Changes in Caco-2 cells proliferation index. c Caco-2 cells’ cycle profiling after modulation (percentages of cells in G0/G1, S and G2/M phases are indicating in the graph according to the graphic legend). d Changes in ROS production in Caco-2 cells (relative fluorescence intensity was normalized to unstimulated control). All data represents three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001

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