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Table 1 The top 12 key pathways according to the degree size in pathway-net

From: Identification of genes and pathways potentially related to PHF20 by gene expression profile analysis of glioblastoma U87 cell line

Pathway name

Style

Outdegreea

Indegreeb

Degreec

MAPK signaling pathway

Up, down

27

3

30

Apoptosis

Down

20

2

22

Pathways in cancer

Up, down

0

21

21

p53 signaling pathway

Up

14

1

15

ErbB signaling pathway

Down

5

6

11

Cytokine–cytokine receptor interaction

Down

11

0

11

Focal adhesion

Down

5

5

10

Jak-STAT signaling pathway

Down

5

4

9

Pancreatic cancer

Up, down

2

6

8

mTOR signaling pathway

Down

4

3

7

Glioma

Up, down

2

5

7

VEGF signaling pathway

Down

4

3

7

  1. aOutdegree indicates the down-stream pathway numbers
  2. bIndegree indicates the up-stream pathway numbers
  3. cDegree indicates the sum of outdegree and indegree