Fig. 5
The impacts of miR-485-5p/NUDT1 axis on eradicating 8-oxo-dG in GC cells. The 8-oxo-dG in the nucleotide pools was detected by immunofluorescence. When NUDT1 was up-regulated by plasmid or miR-485-5p inhibitors, the 8-oxo-dG in nucleus and cytoplasm decreased; while the level of 8-oxo-dG increased after the knockdown of NUDT1. PCDNA NUDT1 refers to overexpression plasmid, and PCDNA NC refers to control plasmid