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Fig. 2 | Cancer Cell International

Fig. 2

From: The impact of γ-irradiation on the induction of bystander killing by genetically engineered ovarian tumor cells: implications for clinical use

Fig. 2

In vitro bystander killing induced by γ-irradiated (100 Gy) mouse mesothelioma AE17-STK cells. a AE17-STK and AE-17 cells (with or without γ-irradiation) were mixed and cultured in the presence of 50 μM GCV for 6 days. The total number of cells was 5 × 104/well of 96-well tissue culture plate. Per cent survival was measured using the MTT assay. Each point is the mean of three separate measurements and error bars indicating the standard error of the mean are shown. Similar data was obtained in three separate experiments. b In vitro bystander killing induced by the γ-irradiated human mesothelioma cell line CRL-5830TK. CRL5830-STK and CRL5830 cells were mixed in the indicated ratios and cultured in the presence of 50 μM GCV for 6 days. The total number of cells was 5 × 104/well of 96-well tissue culture plate. The fraction of surviving cells was measured using the MTT assay. Each point is the mean of three separate measurements and error bars indicate the standard error of the mean. Similar data was obtained in three separate experiments

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