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Fig. 4 | Cancer Cell International

Fig. 4

From: miR-1296-5p decreases ERBB2 expression to inhibit the cell proliferation in ERBB2-positive breast cancer

Fig. 4

MiR-1296-5p suppresses mTORC1 signaling. a, b miR-1296-5p overexpression did not alter the activation of RhoA and Rac1 in SK-BR-3 breast cancer cells. The RhoA or Rac1 relative active levels were normalized to the average value of SK-BR-3 cells transfected with control miRNA. ns, no significance. c, d miR-1296-5p overexpression suppresses the phosphorylation of S6 in SK-BR-3 or BT-474 breast cancer cells

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Cancer Cell International

ISSN: 1475-2867

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