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Fig. 1 | Cancer Cell International

Fig. 1

From: miR-155-5p modulates malignant behaviors of hepatocellular carcinoma by directly targeting CTHRC1 and indirectly regulating GSK-3β-involved Wnt/β-catenin signaling

Fig. 1

Expression of miR-155-5p and CTHRC1 in the para-carcinoma tissue and carcinoma tissue of HCC patients. a miR-155-5p expression was analyzed by qRT-PCR in the para-carcinoma tissue and carcinoma tissue of HCC patients. miR-155-5p was significantly down-regulated in carcinoma tissue. “p” indicates patient. *p < 0.05. b CTHRC1 mRNA expression was detected by qRT-PCR in the para-carcinoma tissue and carcinoma tissue of HCC patients. CTHRC1 was remarkably up-regulated in carcinoma tissue. *p < 0.05. c Immunohistochemical staining of CTHRC1 in the para-carcinoma tissue and carcinoma tissue of HCC patients (× 200 magnification). The red arrow represents positive staining of CTHRC1, which was mainly located in cytoplasm. d CTHRC1 protein expression was tested by WB in the para-carcinoma tissue and carcinoma tissue of HCC patients. CTHRC1 was notably elevated in carcinoma tissue. *p < 0.05

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