|
Parameter
|
n
|
Low miR-214-3p expression
|
High miR-214-3p expression
|
P
|
|---|
|
Age
|
98
|
56.60 ± 6.14
|
54.06 ± 8.73
|
0.327*
|
|
Gender
|
|
Male
|
83
|
44
|
39
|
0.742#
|
|
Female
|
15
|
6
|
9
| |
|
Liver disease
|
|
HBV
|
93
|
46
|
47
|
1.000∆
|
|
Others
|
5
|
3
|
2
| |
|
Cirrhosis
|
|
Positive
|
94
|
46
|
48
|
1.000∆
|
|
Negative
|
4
|
2
|
2
| |
|
Tumor stage
|
|
I + II
|
65
|
32
|
33
|
0.791#
|
|
III
|
33
|
18
|
15
| |
|
Histologic grade
|
|
Differentiated
|
87
|
41
|
46
|
0.068∆
|
|
Undifferentiated
|
11
|
8
|
3
| |
|
Milan criteria
|
|
In
|
53
|
23
|
30
|
0.163#
|
|
Out
|
45
|
26
|
19
| |
|
Tumor size (cm)
|
|
≤ 4.5
|
59
|
24
|
35
|
0.016#
|
|
> 4.5
|
39
|
25
|
14
| |
|
Multinodular
|
|
Positive
|
43
|
25
|
18
|
0.044#
|
|
Negative
|
55
|
24
|
31
| |
|
Vascular invasion
|
|
Positive
|
22
|
16
|
6
|
0.025#
|
|
Negative
|
77
|
33
|
43
| |
|
Serum AFP (ng/ml)
|
|
≤ 400
|
62
|
29
|
33
|
1.000#
|
|
> 400
|
36
|
19
|
17
| |
|
Overall survival
|
41/98
|
11/49
|
30/49
| |
|
HCC recurrence
|
57/98
|
37/49
|
20/49
| |
-
AFP alpha-fetoprotein
-
* Unpaired student t-test; #Chi square test; ∆Fisher’s exact test
