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Table 1 Correlation of Gas5 expression with clinicopathological features of patients with CRC

From: Effect of long non-coding RNA Gas5 on proliferation, migration, invasion and apoptosis of colorectal cancer HT-29 cell line

Clinicopathological features N Gas5 mRNA expression P Gas5 protein expression P
Age (years)
 ≤ 60 79 0.59 ± 0.20 0.162 0.46 ± 0.14 0.691
 > 60 47 0.54 ± 0.18   0.47 ± 0.13  
Gender
 Male 74 0.56 ± 0.20 0.582 0.45 ± 0.11 0.214
 Female 52 0.58 ± 0.20   0.48 ± 0.16  
Tumor size (cm)
 ≤ 5 45 0.64 ± 0.19 0.002 0.53 ± 0.15 < 0.001
 > 5 81 0.53 ± 0.19   0.42 ± 0.10  
Invasive depth
 T1 28 0.62 ± 0.22 0.185 0.47 ± 0.14 0.053
 T2 44 0.59 ± 0.18   0.50 ± 0.15  
 T3 35 0.54 ± 0.21   0.44 ± 0.11  
 T4 19 0.50 ± 0.16   0.41 ± 0.10  
Lymph node metastasis
 With 67 0.55 ± 0.17 0.153 0.45 ± 0.14 0.202
 Without 59 0.60 ± 0.22   0.48 ± 0.12  
Distant metastasis
 With 80 0.55 ± 0.21 0.107 0.45 ± 0.12 0.103
 Without 46 0.61 ± 0.18   0.49 ± 0.15  
Tumor differentiation
 Well or moderate differentiation 74 0.55 ± 0.21 0.158 0.47 ± 0.13 0.412
 Poor or no differentiation 52 0.60 ± 0.18   0.45 ± 0.14  
TNM staging
 I–II 60 0.66 ± 0.19 < 0.001 0.49 ± 0.12 < 0.034
 III–IV 66 0.49 ± 0.17   0.44 ± 0.14  
Tumor site
 Right hemicolon 68 0.58 ± 0.20 0.577 0.46 ± 0.15 0.684
 Left hemicolon 58 0.56 ± 0.20   0.47 ± 0.12  
  1. Gas5 growth arrest-specific transcript 5, CRC colorectal cancer, TNM tumor-node-metastasis