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Table 1 Correlation of Gas5 expression with clinicopathological features of patients with CRC

From: Effect of long non-coding RNA Gas5 on proliferation, migration, invasion and apoptosis of colorectal cancer HT-29 cell line

Clinicopathological features

N

Gas5 mRNA expression

P

Gas5 protein expression

P

Age (years)

 ≤ 60

79

0.59 ± 0.20

0.162

0.46 ± 0.14

0.691

 > 60

47

0.54 ± 0.18

 

0.47 ± 0.13

 

Gender

 Male

74

0.56 ± 0.20

0.582

0.45 ± 0.11

0.214

 Female

52

0.58 ± 0.20

 

0.48 ± 0.16

 

Tumor size (cm)

 ≤ 5

45

0.64 ± 0.19

0.002

0.53 ± 0.15

< 0.001

 > 5

81

0.53 ± 0.19

 

0.42 ± 0.10

 

Invasive depth

 T1

28

0.62 ± 0.22

0.185

0.47 ± 0.14

0.053

 T2

44

0.59 ± 0.18

 

0.50 ± 0.15

 

 T3

35

0.54 ± 0.21

 

0.44 ± 0.11

 

 T4

19

0.50 ± 0.16

 

0.41 ± 0.10

 

Lymph node metastasis

 With

67

0.55 ± 0.17

0.153

0.45 ± 0.14

0.202

 Without

59

0.60 ± 0.22

 

0.48 ± 0.12

 

Distant metastasis

 With

80

0.55 ± 0.21

0.107

0.45 ± 0.12

0.103

 Without

46

0.61 ± 0.18

 

0.49 ± 0.15

 

Tumor differentiation

 Well or moderate differentiation

74

0.55 ± 0.21

0.158

0.47 ± 0.13

0.412

 Poor or no differentiation

52

0.60 ± 0.18

 

0.45 ± 0.14

 

TNM staging

 I–II

60

0.66 ± 0.19

< 0.001

0.49 ± 0.12

< 0.034

 III–IV

66

0.49 ± 0.17

 

0.44 ± 0.14

 

Tumor site

 Right hemicolon

68

0.58 ± 0.20

0.577

0.46 ± 0.15

0.684

 Left hemicolon

58

0.56 ± 0.20

 

0.47 ± 0.12

 
  1. Gas5 growth arrest-specific transcript 5, CRC colorectal cancer, TNM tumor-node-metastasis