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Fig. 1 | Cancer Cell International

Fig. 1

From: Pharmacological inhibition of Bmi1 by PTC-209 impaired tumor growth in head neck squamous cell carcinoma

Fig. 1

Overexpression of Bmi1 mRNA in a subset of HNSCC. a Transcriptional landscape of Bmi1 in a broad spectrum of human cancers as compared to the corresponding normal tissue was revealed using GENT database consisting of the cancer profiling data using U133Plus2 platform. X-axis represents the pairs of cancer and corresponding normal counterparts. Y-axis represents the log2 median–centered intensity. The mRNA levels of Bmi1 were compared between HNSCC samples and normal counterparts in Toruner’s (b) and Ginos’s (c) patient cohorts. The original data were retrieved from Oncomine database and plotted using Graphpad Prism 6.0 software. Y-axis represents the median intensity, 25th and 75th percentile data. **p < 0.01, Student-t test for Toruner’s data and Mann–Whitney U test for Ginos’s data

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