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Fig. 6 | Cancer Cell International

Fig. 6

From: Pharmacological inhibition of Bmi1 by PTC-209 impaired tumor growth in head neck squamous cell carcinoma

Fig. 6

PTC-209 administration impairs tumor growth in a HNSCC xenograft model. a Volume changes in tumor masses harvested from PTC-209-treated (30 mg/kg, 15 days) animals and vehicle-treated animals were detected and compared. b Final weight of tumor masses harvested from PTC-209-treated animals and vehicle-treated animals was compared. c Immunohistochemical staining of Bmi1 and Ki67 in samples harvested from PTC-209-treated animals and vehicle-treated animals. Scale bar: 100 μm. d Immunoflurescent staining of CSCs surface marker CD44 in samples harvested from PTC-209-treated animals and vehicle-treated animals. Scale bar: 100 μm. Representative images are shown. *p < 0.05, **p < 0.01, Student’s t test

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