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Table 1 Coding regions representing deleterious amino acid mutations in NNK-treated, low phalloidin-binding, WM9 subclones

From: The human, F-actin-based cytoskeleton as a mutagen sensor

HUGO symbol of CPCR coding region

WM9-5F

WM9-2R

WM9-3R

DNAH11

 

1 unique

1 unique

MUC16

1 unique

1 shared with 3R

1 unique

1 unique

1 shared with 5F

TTN

  

1 unique

XIRP2

2 shared with 2R

2 shared with 5F

 
  1. No deleterious amino acid alterations were detected in the high phalloidin binding, WM9-1F and WM9-3F subclones; shared mutations indicated in italics. The three low phalloidin binding subclones (WM9-3R -2R, and -5F) represent a total of 12 deleterious amino acid changes, based on the PROVEAN tool (see Additional file 8)
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Cancer Cell International

ISSN: 1475-2867

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