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Fig. 6 | Cancer Cell International

Fig. 6

From: Matrine combined with cisplatin synergistically inhibited urothelial bladder cancer cells via down-regulating VEGF/PI3K/Akt signaling pathway

Fig. 6

Effect of matrine and cisplatin alone and in combination on apoptosis. Representative profiles showing apoptosis in EJ (a) and T24 (b) cells treated with 5 mM of matrine, 4 μM of cisplatin alone and 1 μM of cisplatin and 2 mM of matrine in combination for 48 h. Histograms represent the average apoptosis rate of EJ (c) and T24 (d). All data are shown as the mean ± SD of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001, or ****P < 0.0001 versus the control group

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