Fig. 4

Knockdown of LINC01510 induced G0/G1-phase arrest in colorectal cancer cells. a, b Detection for cell cycle of CRC cells after silencing and overexpression of LINC01510 expression in LoVo and SW620 cells. Results are expressed as peak diagram (a) and calculated distribution for cells in G0/G1 phases (b). c, d The apoptosis protein expression of CDK2 and P21 in LoVo and SW620 cells with LINC01510 overexpression and knockdown. Results are expressed as blot diagram (c) and gray intensity calculated (d) expression of CDK2 and P21. Data were based on at least three independent experiments and shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001