Fig. 2

a Densitometric analysis of Western blotting shows also in this case a significant decrease of TrxR1 expression (− 49 ± 1.2%, p < 0.01) in cancer (red line) with respect to the healthy thyroid tissue (black line). b Western blotting analysis of TrxR1 and actin in cancer (C) and healthy (H) thyroid tissue shows a general reduction of TrxR1 in cancer (C). The numbers below identify the patient (see Table 1). NS not significant, *p < 0.01