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Fig. 3 | Cancer Cell International

Fig. 3

From: SHP-2 restricts apoptosis induced by chemotherapeutic agents via Parkin-dependent autophagy in cervical cancer

Fig. 3

Effect of SHP-2 on mitochondria damage in cervical cancer cells. Hela cells were transfected SHP-2 shRNA1 and treated CCCP (10 μM). a The change of ΔΨm was detected by confocal laser scanning microscope using JC-1 staining. b The Ca2+ level in cytoplasm was detected by flow cytometry. c, d Intracellular ROS levels was measured by flow cytometry. Data are presented as mean ± SD. **P < 0.01

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